Does the locus on chromosome 11 implicated in susceptibility to HLA-DR4 dependent type I diabetes mellitus also affect susceptibility to rheumatoid arthritis?
There is a polygenic component to rheumatoid arthritis (RA) in addition to the known association with HLA-DR4. It has previously been shown in another autoimmune disease (type I diabetes mellitus) that a gene on chromosome 11p can act with HLA-DR4 to enhance susceptibility (relative risk 5-6). It is...
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| Published in: | Ann Rheum Dis |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BMJ Publishing Group
1992
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1012466/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1466604/ https://ncbi.nlm.nih.govhttps://doi.org/10.1136/ard.51.11.1250 |
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