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Mechanisms of ALA-D inhibition by lead and of its restoration by zinc and dithiothreitol.

To induce the inhibition of ALA-D (delta-aminolaevulinic acid dehydratase) activity by lead in vitro, it is necessary to preincubate the enzyme fraction with lead ions and the Hb fraction (factors) together. The combination of two of the three (ALA-D fraction, lead acetate, and Hb fraction) in the p...

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Bibliographic Details
Main Authors: Sakai, T, Yanagihara, S, Kunugi, Y, Ushio, K
Format: Artigo
Language:Inglês
Published: 1983
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1009119/
https://ncbi.nlm.nih.gov/pubmed/6824601
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