Ca(2+)-mediated activation of ERK in hepatocytes by norepinephrine and prostaglandin F(2α): role of calmodulin and src kinases

BACKGROUND: Previous studies have shown that several agents that stimulate heptahelical G-protein coupled receptors activate the extracellular signal regulated kinases ERK1 (p44(mapk)) and ERK2 (p42(mapk)) in hepatocytes. The molecular pathways that convey their signals to ERK1/2 are only partially...

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Bibliographic Details
Main Authors: Melien, Øyvind, Nilssen, Laila S, Dajani, Olav F, Sand, Kristin Larsen, Iversen, Jens-Gustav, Sandnes, Dagny L, Christoffersen, Thoralf
Format: Artigo
Language:Inglês
Published: BioMed Central 2002
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC100782/
https://ncbi.nlm.nih.gov/pubmed/11914123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-3-5
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