Oxidative DNA damage and cellular sensitivity to oxidative stress in human autoimmune diseases.

OBJECTIVES--To estimate the extent of genomic DNA damage and killing of lymphocytes by reactive oxygen intermediates in autoimmune diseases. METHODS--8-Oxo-7-hydrodeoxyguanosine (8-oxodG), a promutagenic DNA lesion induced by reactive oxygen intermediates, was measured by high performance liquid chr...

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Autors principals: Bashir, S, Harris, G, Denman, M A, Blake, D R, Winyard, P G
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1005143/
https://ncbi.nlm.nih.gov/pubmed/8239761
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