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Identification of tissue inhibitor of metalloproteinase-2 (TIMP-2)-progelatinase complex as the third metalloproteinase inhibitor peak in rheumatoid synovial fluid.

The metalloproteinases are a family of enzymes that can degrade all the components of the extracellular matrix. These potent enzymes are often found in proenzyme forms and require activation before the substrate can be digested. To prevent unlimited connective tissue destruction a number of inhibito...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cawston, T E, Bigg, H F, Clark, I M, Hazleman, B L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1005013/
https://ncbi.nlm.nih.gov/pubmed/8484669
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