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Cartilage degradation by polymorphonuclear leucocytes: in vitro assessment of the pathogenic mechanisms.

Polymorphonuclear leucocytes (PMNs), which predominate in inflammatory synovial fluid, can degrade cartilage. This was measured by a novel in vitro model; PMNs were incubated for up to one hour with 2 or 3 microns sections of cartilage and the glycosaminoglycan loss determined by microdensitometry a...

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Main Authors: Moore, A R, Iwamura, H, Larbre, J P, Scott, D L, Willoughby, D A
格式: Artigo
語言:Inglês
出版: 1993
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1004951/
https://ncbi.nlm.nih.gov/pubmed/8427510
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