Localisation and characterisation of substance P binding to human synovial tissue in rheumatoid arthritis.

The neuropeptide substance P is found in perivascular and free unmyelinated nerve fibres in human synovial tissue. Quantitative receptor autoradiography was used to show specific, high affinity (Kd = 0.75 (0.21), nmol/l (mean (standard error of the mean)), low capacity (Bmax = 27.8 (7.9) amol/mm2) b...

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Main Authors: Walsh, D A, Mapp, P I, Wharton, J, Rutherford, R A, Kidd, B L, Revell, P A, Blake, D R, Polak, J M
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1004650/
https://ncbi.nlm.nih.gov/pubmed/1374227
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