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Effects of pyrazinamide, probenecid, and benzbromarone on renal excretion of oxypurinol.

The effects of pyrazinamide, probenecid, and benzbromarone on renal excretion of oxypurinol were investigated. Pyrazinamide decreased the mean (SEM) fractional clearance of oxypurinol from 19.2 (2.1) to 8.8 (1.5). Probenecid increased the fractional clearance of oxypurinol from 14.1 (3.5) to 24.8 (4...

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Autores principales: Yamamoto, T, Moriwaki, Y, Takahashi, S, Suda, M, Higashino, K
Formato: Artigo
Lenguaje:Inglês
Publicado: 1991
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1004507/
https://ncbi.nlm.nih.gov/pubmed/1929586
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