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Influence of C4 null alleles on C4 activation in systemic lupus erythematosus.

Deficiencies of early components of the classical complement pathway are known to be associated with systemic lupus erythematosus (SLE). C4 null alleles, C4A Q0 and C4B Q0, are prime candidates for the major histocompatibility complex associated factor which determines susceptibility to SLE. There i...

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Bibliographic Details
Main Authors: Briggs, D C, Senaldi, G, Isenberg, D A, Welsh, K I, Vergani, D
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1004396/
https://ncbi.nlm.nih.gov/pubmed/2029208
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