Lymphocytotoxic antibodies in systemic lupus erythematosus: studies of their temperature dependence, binding characteristics, and specificity in vitro.

The lymphocytotoxicity of 33 lupus sera was tested against purified helper/inducer (OKT4) and cytotoxic/suppressor (OKT8) subsets of T lymphocytes at 15 degrees C and 37 degrees C in vitro. There was significantly less killing of both OKT4 and OKT8 cells at 37 degrees C (p less than 0.001 and p less...

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Detalhes bibliográficos

Publicado no:	Ann Rheum Dis
Principais autores:	Peake, P W, Greenstein, J D, Timmermans, V, Gavrilovic, L, Charlesworth, J A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMJ Publishing Group 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1003588/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3178313/ https://ncbi.nlm.nih.govhttps://doi.org/10.1136/ard.47.9.725
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