A monoclonal antibody raised by immunising mice with group A streptococci binds to agalactosyl IgG from rheumatoid arthritis.
It was shown recently that the IgG of patients with rheumatoid arthritis tends to lack the terminal galactose normally present on the conserved N-linked oligosaccharide situated on the CH2 domain. This results in the exposure of a terminal N-acetylglucosamine linked beta 1-2 to mannose. It is report...
Shranjeno v:
| izdano v: | Ann Rheum Dis |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BMJ Publishing Group
1988
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1003493/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2451483/ https://ncbi.nlm.nih.govhttps://doi.org/10.1136/ard.47.3.247 |
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