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GATA-4 interacts distinctively with negative and positive regulatory elements in the Fgf-3 promoter

GATA-4 binds two sites in the Fgf-3 promoter, PS4A and PS13, which function as positive and negative regulatory elements, respectively. In spite of their opposite functions, both PS4A and PS13 acted as potent enhancer elements when three copies of each were appended to a minimal tk promoter. Mutatio...

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Bibliographic Details
Main Authors: Murakami, Akira, Ishida, Sanami, Dickson, Clive
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC100337/
https://ncbi.nlm.nih.gov/pubmed/11842118
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