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In vitro transcription of a torsionally constrained template

RNA polymerase (RNAP) and the DNA template must rotate relative to each other during transcription elongation. In the cell, however, the components of the transcription apparatus may be subject to rotary constraints. For instance, the DNA is divided into topological domains that are delineated by ro...

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Detalhes bibliográficos
Main Authors: Bentin, Thomas, Nielsen, Peter E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC100306/
https://ncbi.nlm.nih.gov/pubmed/11809894
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