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Efficient polyadenylation of Rous sarcoma virus RNA requires the negative regulator of splicing element

Rous sarcoma virus pre-mRNA contains an element known as the negative regulator of splicing (NRS) that acts to inhibit viral RNA splicing. The NRS binds serine/arginine-rich (SR) proteins, hnRNP H and the U1/U11 snRNPs, and appears to inhibit splicing by acting as a decoy 5′ splice site. Deletions w...

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Bibliographic Details
Main Authors: Fogel, Brent L., McNally, Lisa M., McNally, Mark T.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC100303/
https://ncbi.nlm.nih.gov/pubmed/11809895
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