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Imbalance of tRNA(Pro) isoacceptors induces +1 frameshifting at near-cognate codons

Increased expression of the CCU/CCA/CCG-decoding tRNA(Pr)(o)(3) on a multicopy plasmid leads to suppression of several +1 frameshift mutations in Salmonella enterica serovar Typhimurium. Systematic analysis of the site of frameshifting indicates that excess tRNA(Pr)(o)(3) promotes near-cognate decod...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Author: O’Connor, Michael
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100296/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11809889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.3.759
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