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Studies in laboratory animals to assess the safety of anti-inflammatory agents in acute porphyria.

The safety of various anti-inflammatory drugs in acute porphyria was assessed by examining their effect on rat hepatic haem synthesis. Azapropazone, chloroquine, and gold increased delta-aminolaevulinic acid (ALA) synthase activity, indicating that they are liable to precipitate porphyric crises. As...

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Bibliographic Details
Main Authors: McColl, K E, Thompson, G G, Moore, M R
Format: Artigo
Language:Inglês
Published: 1987
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1002189/
https://ncbi.nlm.nih.gov/pubmed/3662642
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