Complement fixation by anti-dsDNA antibodies in SLE: measurement by radioimmunoassay and relationship with disease activity.

We have developed a sensitive, solid phase radioimmunoassay (RIA) to quantify the amount of complement (C') fixation by anti-double-stranded DNA (anti-dsDNA) antibodies and have studied sera from 48 patients with systemic lupus erythematosus (SLE). 46% of the patients were positive in this assay. Th...

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Detalhes bibliográficos

Publicado no:	Ann Rheum Dis
Principais autores:	Mackworth-Young, C G, Chan, J K, Bunn, C C, Hughes, G R, Gharavi, A E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMJ Publishing Group 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1001875/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3486639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1136/ard.45.4.314
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