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Effect of acetylator phenotype on efficacy and toxicity of sulphasalazine in rheumatoid arthritis.

A group of 54 patients with rheumatoid arthritis (31 fast, 23 slow acetylators) treated with sulphasalazine 3 g/day were studied retrospectively. At 24 weeks no difference in the efficacy of the drug could be shown between fast and slow acetylators. In a second prospective study 40 fast acetylators...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Principais autores: Pullar, T, Hunter, J A, Capell, H A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1001793/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2867746/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/ard.44.12.831
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