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Oxygen free-radicals mediate an inhibition of proteoglycan synthesis in cultured articular cartilage.

Superoxide radical, generated enzymatically by the action of xanthine oxidase on hypoxanthine, significantly inhibited proteoglycan synthesis by cultured bovine articular cartilage. This inhibition was not due to the generation of uric acid or to the generation of superoxide per se. It was immediate...

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Hlavní autoři: Bates, E J, Lowther, D A, Handley, C J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1984
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1001371/
https://ncbi.nlm.nih.gov/pubmed/6331328
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