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Diminished Virulence of an Alpha-Toxin Mutant of Staphylococcus aureus in Experimental Brain Abscesses

Staphylococcus aureus is one of the major etiologic agents of brain abscesses in humans, occasionally leading to focal neurological deficits and even death. The objective of the present study was to identify key virulence determinants contributing to the pathogenesis of S. aureus in the brain using...

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Published in:Infect Immun
Main Authors: Kielian, Tammy, Cheung, Ambrose, Hickey, William F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2001
Subjects:
Bacterial Infections
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100070/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11598065/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.11.6902-6911.2001
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