Bordetella pertussis Autoregulates Pertussis Toxin Production through the Metabolism of Cysteine

Pertussis toxin (Ptx) expression and secretion in Bordetella pertussis are regulated by a two-component signal transduction system encoded by the bvg regulatory locus. However, it is not known whether the metabolic pathways and growth state of the bacterium influence synthesis and secretion of Ptx a...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Bogdan, John A., Nazario-Larrieu, Javier, Sarwar, Jawad, Alexander, Peter, Blake, M. S.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2001
Subjects:	Molecular Pathogenesis
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100060/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11598055/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.11.6823-6830.2001
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