Effects of Alum Adjuvant or a Booster Dose on Immunogenicity during Clinical Trials of Group B Streptococcal Type III Conjugate Vaccines

Phase 1 and 2 clinical trials of group B streptococcal (GBS) capsular polysaccharide (CPS)-protein conjugate vaccines in healthy adults have demonstrated their safety and improved immunogenicity compared with uncoupled CPSs. Two recent trials sought to determine (i) whether adsorption of conjugate v...

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Detalhes bibliográficos
Main Authors: Paoletti, L. C., Rench, M. A., Kasper, D. L., Molrine, D., Ambrosino, D., Baker, C. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC100045/
https://ncbi.nlm.nih.gov/pubmed/11598040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.11.6696-6701.2001
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