Enhanced Antimycobacterial Response to Recombinant Mycobacterium bovis BCG Expressing Latency-Associated Peptide

With a view to exploring the role of transforming growth factor β (TGF-β) during mycobacterial infection, recombinant clones of bacillus Calmette-Guérin (BCG) were engineered to express the natural antagonist of TGF-β, latency-activated peptide (LAP). Induction of TGF-β activity was reduced when mac...

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Autors principals: Marshall, Ben G., Wangoo, Arun, O'Gaora, Peadar, Cook, H. Terry, Shaw, Rory J., Young, Douglas B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC100042/
https://ncbi.nlm.nih.gov/pubmed/11598037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.11.6676-6682.2001
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