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Identification of p53 Sequence Elements That Are Required for MDM2-Mediated Nuclear Export

It has been demonstrated that MDM2 can differentially regulate subcellular distribution of p53 and its close structural homologue p73. In contrast to MDM2-mediated p53 nuclear export, p73 accumulates in the nucleus as aggregates that colocalize with MDM2. Distinct distribution patterns of p53 and p7...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Gu, Jijie, Nie, Linghu, Wiederschain, Dmitri, Yuan, Zhi-Min
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100016/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11713288/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.24.8533-8546.2001
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