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Atomic layer deposition coating of carbon nanotubes with aluminum oxide alters pro-fibrogenic cytokine expression by human mononuclear phagocytes in vitro and reduces lung fibrosis in mice in vivo.
Multi-walled carbon nanotubes (MWCNTs) pose a possible human health risk for lung disease as a result of inhalation exposure. Mice exposed to MWCNTs develop pulmonary fibrosis. Lung macrophages engulf MWCNTs and produce pro-fibrogenic cytokines including interleukin (IL)-1β, IL-6, tumor necrosis fac...
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Główni autorzy: | , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
Public Library of Science (PLoS)
2014-01-01
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Seria: | PLoS ONE |
Dostęp online: | http://europepmc.org/articles/PMC4162563?pdf=render |
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