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Liquid Chromatography/Tandem Mass Spectrometry Method for Quantitation of Cremophor EL and Its Applications
A rapid sensitive and selective MRM based method for the determination of Cremophor EL (CrEL) in rat plasma was developed using liquid chromatography/tandem mass spectrometry (LC-MS/MS). CrEL and polypropylene glycol (internal standard) were extracted from rat plasma with acetonitrile and analysed o...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
Hindawi Limited
2013-01-01
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Series: | International Journal of Analytical Chemistry |
Acceso en liña: | http://dx.doi.org/10.1155/2013/135613 |
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