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Fibrin-Induced epithelial-to-mesenchymal transition of peritoneal mesothelial cells as a mechanism of peritoneal fibrosis: effects of pentoxifylline.

Excessive fibrin deposition in the peritoneum is thought to be involved in the development of encapsulating peritoneal sclerosis (EPS), an important cause of morbidity and mortality in peritoneal dialysis patients. We investigated fibrin-induced epithelial-to-mesenchymal transition (EMT) of peritone...

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Main Authors: Cheng-Chung Fang, Jenq-Wen Huang, Ren-Shi Shyu, Chung-Jen Yen, Cheng-Hsiang Shiao, Chih-Kang Chiang, Rey-Heng Hu, Tun-Jun Tsai
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2012-01-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC3441450?pdf=render
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