Fibrin-Induced epithelial-to-mesenchymal transition of peritoneal mesothelial cells as a mechanism of peritoneal fibrosis: effects of pentoxifylline.

Excessive fibrin deposition in the peritoneum is thought to be involved in the development of encapsulating peritoneal sclerosis (EPS), an important cause of morbidity and mortality in peritoneal dialysis patients. We investigated fibrin-induced epithelial-to-mesenchymal transition (EMT) of peritone...

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Hauptverfasser: Cheng-Chung Fang, Jenq-Wen Huang, Ren-Shi Shyu, Chung-Jen Yen, Cheng-Hsiang Shiao, Chih-Kang Chiang, Rey-Heng Hu, Tun-Jun Tsai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC3441450?pdf=render
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