miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

<p>Abstract</p> <p>Background</p> <p>Glioblastoma multiforme (GBM) is an invariably fatal central nervous system tumor despite treatment with surgery, radiation, and chemotherapy. Further insights into the molecular and cellular mechanisms that drive GBM formation are r...

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Auteurs principaux: Costello Joseph F, James C David, Ginzinger David G, Vandenberg Scott R, Yu Mamie, Maunakea Alika K, Persson Anders I, Petritsch Claudia, Lim Daniel A, Silber Joachim, Bergers Gabriele, Weiss William A, Alvarez-Buylla Arturo, Hodgson J Graeme
Format: Artigo
Langue:Inglês
Publié: BMC 2008-06-01
Collection:BMC Medicine
Accès en ligne:http://www.biomedcentral.com/1741-7015/6/14
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