microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasion.

Metastatic renal cancer manifests multiple signatures of gene expression. Deviation in expression of mature miRNAs has been linked to human cancers. Importance of miR-21 in renal cell carcinomas is proposed from profiling studies using tumor tissue samples. However, the role of miR-21 function in ca...

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Hauptverfasser: Nirmalya Dey, Falguni Das, Nandini Ghosh-Choudhury, Chandi Charan Mandal, Dipen J Parekh, Karen Block, Balakuntalam S Kasinath, Hanna E Abboud, Goutam Ghosh Choudhury
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC3368259?pdf=render
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