Long-term bisphosphonate treatment coupled with ovariectomy in mice provokes deleterious effects on femoral neck fracture pattern and modifies tibial shape

Aims: The processes linking long-term bisphosphonate treatment to atypical fracture remain elusive. To establish a means of exploring this link, we have examined how long-term bisphosphonate treatment with prior ovariectomy modifies femur fracture behaviour and tibia mass and shape in murine bones....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Samuel Monzem, Rafael Y. Ballester, Behzad Javaheri, Blandine Poulet, Dábila A. Sônego, Andrew A. Pitsillides, Roberto L. Souza
Format: Artigo
Sprache:Inglês
Veröffentlicht: The British Editorial Society of Bone & Joint Surgery 2020-09-01
Schriftenreihe:Bone & Joint Open
Schlagworte:
bone quality
bone strength
ibandronate
biomechanical properties
bone geometry
Online Zugang:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2633-1462.19.BJO-2020-0117.R1
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