The crosstalk between vascular MSCs and inflammatory mediators determines the pro-calcific remodelling of human atherosclerotic aneurysm

Abstract Background Human mesenchymal stem cells (MSCs) possess well-known reparative abilities, but any defect of the immunomodulatory activity and/or the differentiation process may determine the development of human diseases, including those affecting the vascular wall. MSCs residing within the h...

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Detalhes bibliográficos
Main Authors: Carmen Ciavarella, Enrico Gallitto, Francesca Ricci, Marina Buzzi, Andrea Stella, Gianandrea Pasquinelli
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-04-01
Colecção:Stem Cell Research & Therapy
Assuntos:
Human aortic mesenchymal stem cells
Inflammation
Calcification
Vascular remodelling
Angiogenesis
Atherosclerotic aneurysm
Acesso em linha:http://link.springer.com/article/10.1186/s13287-017-0554-x
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