Targeted Therapy Against the Cell of Origin in Cutaneous Squamous Cell Carcinoma

Squamous cell carcinomas (SCC), including cutaneous SCCs, are by far the most frequent cancers in humans, accounting for 80% of all newly diagnosed malignancies worldwide. The old dogma that SCC develops exclusively from stem cells (SC) has now changed to include progenitors, transit-amplifying and...

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Bibliographic Details
Main Authors: Stephen J. Goldie, Ginevra Chincarini, Charbel Darido
Format: Artigo
Language:Inglês
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
Squamous cell carcinoma
cell of origin
differentiated cells
stem cells
cancer stem cells
therapeutic targets
Online Access:https://www.mdpi.com/1422-0067/20/9/2201
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