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Targeting Oncogenic Signaling in Mutant FLT3 Acute Myeloid Leukemia: The Path to Least Resistance

The identification of recurrent driver mutations in genes encoding tyrosine kinases has resulted in the development of molecularly-targeted treatment strategies designed to improve outcomes for patients diagnosed with acute myeloid leukemia (AML). The receptor tyrosine kinase FLT3 is the most common...

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Detalhes bibliográficos
Main Authors: Dilana Staudt, Heather C. Murray, Tabitha McLachlan, Frank Alvaro, Anoop K. Enjeti, Nicole M. Verrills, Matthew D. Dun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2018-10-01
Colecção:International Journal of Molecular Sciences
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Acesso em linha:http://www.mdpi.com/1422-0067/19/10/3198
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