IL-12 can target human lung adenocarcinoma cells and normal bronchial epithelial cells surrounding tumor lesions.

BACKGROUND: Non small cell lung cancer (NSCLC) is a leading cause of cancer death. We have shown previously that IL-12rb2 KO mice develop spontaneously lung adenocarcinomas or bronchioalveolar carcinomas. Aim of the study was to investigate i) IL-12Rbeta2 expression in human primary lung adenocarcin...

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Main Authors: Irma Airoldi, Emma Di Carlo, Claudia Cocco, Emanuela Caci, Michele Cilli, Carlo Sorrentino, Gabriella Sozzi, Silvano Ferrini, Sandra Rosini, Giulia Bertolini, Mauro Truini, Francesco Grossi, Luis Juan Vicente Galietta, Domenico Ribatti, Vito Pistoia
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2702099?pdf=render
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