Curcumin ameliorates lipid metabolic disorder and cognitive dysfunction via the ABCA1 transmembrane transport system in APP/PS1 double transgenic mice

The disorder of lipid metabolism, especially cholesterol metabolism, can promote Alzheimer’s Disease. Curcumin can ameliorate lipid metabolic disorder in the brain of Alzheimer’s Disease patients, while the mechanism is not clear. APP/PS1 (APPswe/PSEN1dE9) double transgenic mice were divided into de...

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Detalhes bibliográficos
Main Authors: Mingyuan Tian, Fanlin Zhou, Zhipeng Teng, Chen Wang, Xiong Zhang, Yangyang Wang, Yu Li
Formato: Artigo
Idioma:Inglês
Publicado em: IMR Press 2021-12-01
Colecção:Journal of Integrative Neuroscience
Assuntos:
curcumin
alzheimer's disease
atp binding cassette a1
cholesterol metabolism
transmembrane transport system
Acesso em linha:https://www.imrpress.com/journal/JIN/20/4/10.31083/j.jin2004091
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