Cerebral small vessel disease: targeting oxidative stressas a novel therapeutic strategy?

Cerebral small vessel disease (SVD) is a major contributor to stroke, and a leading cause of cognitive impairment and dementia. Despite the devastating effects of cerebral SVD, the pathogenesis of cerebral SVD is still not completely understood. Moreover, there are no specific pharmacological strate...

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Detalhes bibliográficos
Main Authors: Alyson Anne Miller, T. Michael eDe Silva
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016-03-01
Colecção:Frontiers in Pharmacology
Assuntos:
Brain Injury
cognitive impairment
Cerebral small vessel disease
Oxidative stress and redox regulation
Pharmacological strategies
NADPH oxidases (Noxs)
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00061/full
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