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Targeting Repulsive Guidance Molecule A to Promote Regeneration and Neuroprotection in Multiple Sclerosis
Repulsive guidance molecule A (RGMa) is a potent inhibitor of neuronal regeneration and a regulator of cell death, and it plays a role in multiple sclerosis (MS). In autopsy material from progressive MS patients, RGMa was found in active and chronic lesions, as well as in normal-appearing gray and w...
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Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Elsevier
2015-03-01
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Schriftenreihe: | Cell Reports |
Online Zugang: | http://www.sciencedirect.com/science/article/pii/S2211124715002065 |
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