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RNA-Seq profiling of spinal cord motor neurons from a presymptomatic SOD1 ALS mouse.

Mechanisms involved with degeneration of motor neurons in amyotrophic lateral sclerosis (ALS; Lou Gehrig's Disease) are poorly understood, but genetically inherited forms, comprising ~10% of the cases, are potentially informative. Recent observations that several inherited forms of ALS involve...

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Detalhes bibliográficos
Main Authors: Urmi Bandyopadhyay, Justin Cotney, Maria Nagy, Sunghee Oh, Jing Leng, Milind Mahajan, Shrikant Mane, Wayne A Fenton, James P Noonan, Arthur L Horwich
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3536741?pdf=render
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