Comparative oncology approach to drug repurposing in osteosarcoma.

BACKGROUND:Osteosarcoma is an orphan disease for which little improvement in survival has been made since the late 1980s. New drug discovery for orphan diseases is limited by the cost and time it takes to develop new drugs. Repurposing already approved FDA-drugs can help overcome this limitation. An...

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Hlavní autoři: Alejandro Parrales, Peter McDonald, Megan Ottomeyer, Anuradha Roy, Frank J Shoenen, Melinda Broward, Tyce Bruns, Douglas H Thamm, Scott J Weir, Kathleen A Neville, Tomoo Iwakuma, Joy M Fulbright
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2018-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC5868798?pdf=render
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