New Developments in the Pathogenesis, Therapeutic Targeting, and Treatment of Pediatric Medulloblastoma

Pediatric medulloblastoma (MB) is the most common pediatric brain tumor with varying prognoses depending on the distinct molecular subtype. The four consensus subgroups are WNT, Sonic hedgehog (SHH), Group 3, and Group 4, which underpin the current 2021 WHO classification of MB. While the field of k...

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Hauptverfasser: Francia Y. Fang, Jared S. Rosenblum, Winson S. Ho, John D. Heiss
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2022-05-01
Schriftenreihe:Cancers
Schlagworte:
pediatric brain tumors
medulloblastoma
molecular subtype
chemotherapy
surgery
radiotherapy
Online Zugang:https://www.mdpi.com/2072-6694/14/9/2285
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