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Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort

Abstract Background The gut microbiome is a complex and metabolically active community that directly influences host phenotypes. In this study, we profile gut microbiota using 16S rRNA gene sequencing in 531 well-phenotyped Finnish men from the Metabolic Syndrome In Men (METSIM) study. Results We in...

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Autori principali: Elin Org, Yuna Blum, Silva Kasela, Margarete Mehrabian, Johanna Kuusisto, Antti J. Kangas, Pasi Soininen, Zeneng Wang, Mika Ala-Korpela, Stanley L. Hazen, Markku Laakso, Aldons J. Lusis
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2017-04-01
Serie:Genome Biology
Soggetti:
Host-microbiota interactions
TMAO
Metabolic traits
Serum metabolites
Type 2 diabetes
Accesso online:http://link.springer.com/article/10.1186/s13059-017-1194-2
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