Metformin Mitigates Nickel-Elicited Angiopoietin-Like Protein 4 Expression via HIF-1α for Lung Tumorigenesis

Nickel (Ni), which is a carcinogenic workplace hazard, increases the risk of lung cancer. Angiopoietin-like protein 4 (ANGPTL4) is a multifunctional cytokine that is involved in both angiogenesis and metastasis, but its role in lung cancer is still not clear. In this study, we assessed the role of A...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yu-Ting Kang, Wen-Cheng Hsu, Chu-Chyn Ou, Hui-Chun Tai, Hui-Ting Hsu, Kun-Tu Yeh, Jiunn-Liang Ko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2020-01-01
Cyfres:International Journal of Molecular Sciences
Pynciau:
nickel
angiopoietin-like protein 4
hypoxia-inducible factor 1 alpha
metformin
chemoprevention
Mynediad Ar-lein:https://www.mdpi.com/1422-0067/21/2/619
Tagiau: Ychwanegu Tag
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