Cytochrome P450 enzymes mediated by DNA methylation is involved in deoxynivalenol-induced hepatoxicity in piglets

Deoxynivalenol (DON) is an inevitable contaminant in animal feed and can lead to liver damage, then decreasing appetite and causing growth retardation in piglets. Although many molecular mechanisms are related to hepatoxicity caused by DON, few studies have been done on cytochrome P450 (CYP450) enzy...

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Detalhes bibliográficos
Main Authors: Aimei Liu, Yaqin Yang, Jingchao Guo, Yan Gao, Qinghua Wu, Ling Zhao, Lv-hui Sun, Xu Wang
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Communications Co., Ltd. 2022-06-01
Colecção:Animal Nutrition
Assuntos:
Deoxynivalenol
Hepatoxicity
Growth inhibition
CYP450 enzyme
DNA methylation
Piglet
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2405654522000257
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