mRNA Subtype of Cancer-Associated Fibroblasts Significantly Affects Key Characteristics of Head and Neck Cancer Cells

Head and neck squamous cell carcinomas (HNSCC) belong among severe and highly complex malignant diseases showing a high level of heterogeneity and consequently also a variance in therapeutic response, regardless of clinical stage. Our study implies that the progression of HNSCC may be supported by c...

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Main Authors: Barbora Peltanová, Hana Holcová Polanská, Martina Raudenská, Jan Balvan, Jiří Navrátil, Tomáš Vičar, Jaromír Gumulec, Barbora Čechová, Martin Kräter, Jochen Guck, David Kalfeřt, Marek Grega, Jan Plzák, Jan Betka, Michal Masařík
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2022-05-01
Serija:Cancers
Teme:
cancer
HNSCC
cancer-associated fibroblasts
tumour microenvironment
cell stiffness
Online dostop:https://www.mdpi.com/2072-6694/14/9/2286
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