Hyperactivity, perseveration and increased responding during attentional rule acquisition in the Fragile X mouse model

Attentional deficits and executive function impairments are common to many neurodevelopmental disorders of intellectual disability and autism, including Fragile X syndrome. In the knockout mouse model for Fragile X syndrome, significant changes in synaptic plasticity and connectivity are found in th...

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Detalhes bibliográficos
Main Authors: Ioannis eKramvis, Huibert eMansvelder, Maarten eLoos, Rhiannon eMeredith
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013-11-01
Colecção:Frontiers in Behavioral Neuroscience
Assuntos:
Attention
Learning
Prefrontal Cortex
5-choice serial reaction time task
fragile x
hyperactivity
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2013.00172/full
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