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A new method to detect loss of heterozygosity using cohort heterozygosity comparisons
<p>Abstract</p> <p>Background</p> <p>Loss of heterozygosity (LOH) is an important marker for one of the 'two-hits' required for tumor suppressor gene inactivation. Traditional methods for mapping LOH regions require the comparison of both tumor and patient-mat...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2010-05-01
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| Serie: | BMC Cancer |
| Accesso online: | http://www.biomedcentral.com/1471-2407/10/195 |
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