A new method to detect loss of heterozygosity using cohort heterozygosity comparisons

<p>Abstract</p> <p>Background</p> <p>Loss of heterozygosity (LOH) is an important marker for one of the 'two-hits' required for tumor suppressor gene inactivation. Traditional methods for mapping LOH regions require the comparison of both tumor and patient-mat...

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Huvudupphovsmän: Lea Rod A, Wellwood Jeremy, Wood Peter, Jardine Paul, Green Michael R, Marlton Paula, Griffiths Lyn R
Materialtyp: Artigo
Språk:Inglês
Publicerad: BMC 2010-05-01
Serie:BMC Cancer
Länkar:http://www.biomedcentral.com/1471-2407/10/195
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