Cu(II)-Catalyzed Oxidative Trifluoromethylation of Indoles with KF as the Base

This paper offers an efficient copper-catalyzed oxidative trifluoromethylation of indoles with low-cost CF3SO2Na via C–H activation. Notably, the use of a base is crucial for the trifluoromethylation of indoles. This reaction proceeds efficiently in good to excellent yields and is toleranc...

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Bibliographic Details
Main Authors: Xiaolin Shi, Xiaowei Li, Lina Ma, Dayong Shi
Format: Artigo
Language:Inglês
Published: MDPI AG 2019-03-01
Series:Catalysts
Subjects:
Cu(II) catalyst
Langlois reagent
trifluoromethylation
indole
radical reaction
Online Access:http://www.mdpi.com/2073-4344/9/3/278
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