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Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis

Abstract Ectopic ceramide accumulation in insulin-responsive tissues contributes to the development of obesity and impairs insulin sensitivity. Moreover, pharmacological inhibition of serine palmitoyl transferase (SPT), the first enzyme essential for ceramide biosynthesis using myriocin in rodents r...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ying Li, Chad Lamar Talbot, Bhawna Chandravanshi, Alec Ksiazek, Ayushi Sood, Kamrul Hasan Chowdhury, J. Alan Maschek, James Cox, Adhini Kuppuswamy Satheesh Babu, Henry A. Paz, Pon Velayutham Anandh Babu, David K. Meyerholz, Umesh D. Wankhade, William Holland, E. Shyong Tai, Scott A. Summers, Bhagirath Chaurasia
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Portfolio 2022-05-01
श्रृंखला:Scientific Reports
ऑनलाइन पहुंच:https://doi.org/10.1038/s41598-022-11219-3
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