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Molecular-genetic mapping of zebrafish mutants with variable phenotypic penetrance.

Forward genetic screens in vertebrates are powerful tools to generate models relevant to human diseases, including neuropsychiatric disorders. Variability in phenotypic penetrance and expressivity is common in these disorders and behavioral mutant models, making their molecular-genetic mapping a for...

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Detalhes bibliográficos
Main Authors: Roshan A Jain, Marc A Wolman, Lauren A Schmidt, Harold A Burgess, Michael Granato
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3198425?pdf=render
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